For the best security and user experience we recommend combining Ledger's safety with MetaMask's convenience and usability. To do so, you have to pair and connect your Ledger to MetaMask following the official Ledger's guide by the link. This will allow you to use MetaMask's user-friendly interface to interact with decentralized applications while securely approving transactions on your physical Ledger device.
WARNING:
Do NOT import your seed phrase to MetaMask via the regular 'Import account' feature as this will eliminate the security mechanism of your hardware wallet. Please, carefully follow the steps in the above-mentioned guide.
Once all is set, proceed to the How to connect MetaMask to Primex guide.